KMID : 0379120010290010067
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Korean Journal of Mycology 2001 Volume.29 No. 1 p.67 ~ p.71
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Antioxidative Activity and Structural Analysis of the Steroid Compound from Fomitella fraxinea
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Lee Jong-Seok
Min Tae-Jin Yu Kook-Hyun Bae Kang-Gyu Park Sang-Shin Han Hey-Chul
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Abstract
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A steroid compound, F-1 with antioxidative activity from the fruit bodies of Fomitella fraxinea was isolated by ethyl acetate extraction, silica gel column chromatography, and preparative silica thin layer chromatography. The structure of the compound was determined to be ergosta-7,22-diene-3-one-16¥â-ol by IR, NMR, and GC-Mass. The compound exhibited inhibition on lipid peroxidation of rat liver microsomes, with IC_(50) value of 3.8§¶/§¢.
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